Anxiety, Incontinence, Insomnia, Polypharmacy
Conditions
Keywords
Polypharmacy, Benzodiazepine use, Oxybutynin use, cognition disorders/drug therapy, incontinence
Brief summary
An educational intervention targeting community-dwelling older adults will lead to a reduction in potentially inappropriate prescriptions (e.g. benzodiazepines, oxybutynin). Cessation of potentially inappropriate medications (e.g. benzodiazepines, oxybutynin)will lead to improved cognitive outcomes in older adults.
Detailed description
This study tests the effectiveness of a knowledge transfer tool for empowering patients to engage in collaborative discontinuation of potentially inappropriate medication with their pharmacist and/or physician
Interventions
BEHAVIORALknowledge transfer tool
knowledge transfer tool for empowering patients to engage in collaborative discontinuation of potentially inappropriate medication with their pharmacist and/or physician
Sponsors
Canadian Institutes of Health Research (CIHR)
Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 65 year old human adults * who fill a prescription for at least 5 medications * community dwelling * chronic use (3 months or longer) of at least one potentially inappropriate medication (e.g. benzodiazepine, oxybutynin)
Exclusion criteria
* patients with severe mental illness, dementia and epilepsy * concomitant consumption of any other antipsychotic medication (including lithium, olanzapine, clozapine, quetiapine, risperidone, haloperidol etc.) * concomitant consumption of any antiepileptic (including carbamazepine, valproate, gabapentin, lamotrigine, topiramate, oxcarbazepine etc.) * concomitant consumption of a cholinesterase inhibitor or memantine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete discontinuation of the targeted potentially inappropriate medication (e.g. benzodiazepines, oxybutynin) | 6 months post-intervention |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cognitive function | 6-months post-intervention | Montreal cognitive assessment instrument Rey's auditory verbal learning test (immediate memory, learning, and delayed recall) |
| Sleep efficiency | 6-months | Sleep efficiency as documented with a sleep diary |
| incontinence-related self-efficacy | 6-months post-intervention | incontinence-related self-efficacy as measured with the geriatric self-efficacy index |
| frequency of urinary incontinence episodes | 6-months post-intervention | frequency of urinary incontinence as measured with a 72-hour bladder diary |
Countries
Canada
Outcome results
None listed