Prolongation of Progesterone Supplementation in Antagonist Cycles and Pregnancy Outcomes

The Effect of Progesterone Supplementation During Early Gestations in Patients Treated With Rec FSH/GnRH Antagonist:a Randomized Controlled Trial

Status

Completed

Phases

Phase 1Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01147770

Enrollment

200

Registered

2010-06-22

Start date

2008-09-30

Completion date

2010-06-30

Last updated

2013-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

progesterone, antagonist, rec FSH, IVF, pregnancy

Brief summary

The objective of this study is to evaluate the effect of the prolongation of luteal support on the ongoing pregnancy rate (beyond 12 weeks of gestation )in recFSH/GnRH antagonist cycles.

Interventions

DRUGprogesterone

duration

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 39 Years

Healthy volunteers

Inclusion criteria

* Age equal or less than 39 * Body mass index between 18-29 kg/m2 * Presence of both ovaries * Basal hormonal values on day 2 of the cycle * Embryotransfer day3 or day5 * 1 to 3 cycles

Exclusion criteria

* Endometriosis stage 3 * Polycystic ovarian syndrome * Frozen or testicular sperm

Design outcomes

Primary

Measure	Time frame
ongoing pregnancy rate	up to 2 years

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026