Efficacity, Safety and Cost of Intravenous Morphine Titration Alone or Combined to Ketamine

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01146145

Acronym

KEMO

Enrollment

160

Registered

2010-06-17

Start date

2003-05-31

Completion date

2009-01-31

Last updated

2010-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

postoperative, pain, analgesia, morphine, titration, ketamine

Brief summary

This is a randomised, controlled, double blinded study comparing in the postoperative setting the analgesic efficacy, the safety and the cost in two groups of patients receiving in the postanesthesia care unit either intravenous morphine titration alone or intravenous morphine titration combined to ketamine.

Detailed description

Randomised, controlled, double blinded study comparing in the postoperative setting the analgesic efficacy, the safety and the cost in two groups of patients receiving in the postanesthesia care unit either intravenous morphine titration alone or intravenous morphine titration combined to ketamine

Interventions

DRUGKetamine

intravenous morphine titration combined to ketamine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Age \> 18 yrs * scheduled surgery * General anesthesia * ASA I to III * Able to use a VAS * No psychological disorders, able to speak french

Exclusion criteria

* Age \< 18 yrs * Locoregional anesthesia or analgesia * Allergia to morphine or ketamine * Morphine or ketamine contraindication * Pregnancy or breast-feeding

Design outcomes

Primary

Measure	Time frame	Description
analgesic efficacy	24 h	the analgesic efficacy, in two groups of patients recevieving in the postanesthesia care unit either intravenous morphine titration alone or intravenous morphine titration combined to ketamine

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026