Diabetes
Conditions
Keywords
diabetes,, medicinal plants,, glucose
Brief summary
The purpose of this study was to investigate whether the infusion of a medicinal plant (Cissus verticillata L.) would be effective in reducing glucose levels in blood and saliva of type 2 Diabetes patients.
Detailed description
Type 2 diabetes mellitus is regarded as one of the most prevalent disease of the adult population. In many developing countries, this condition is regarded as major public health problem. Type 2 diabetes is a metabolic disorder characterized by high blood glucose related with a condition of insulin resistance and relative insulin deficiency. As Diabetes progresses, medications are necessary to control glucose levels. The aim of this study was to investigate whether the infusion of a medicinal plant (Cissus verticillata L.) would be as effective as a regular drug (glibenclamide) in reducing glucose levels in blood and saliva of type 2 Diabetes patients. Several medicinal plants have been used as potential medication for controlling glucose levels in Diabetes patients. Few studies have explored this effect related to Cissus verticillata L.infusion, though it has been indicated by folk medicine of some Latin American countries.
Interventions
DRUGglibenclamide
5 mg as pills, taken daily during the morning for 60 days
OTHERmedicinal plant infusion
INfusion fo Cissus verticillata L., 1 g in 150 mL water, ingested daily for 60 days.
Sponsors
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Federal University of Paraíba
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* subjects of 30 up to 80 years of age * positive diagnostic for type 2 diabetes mellitus (blood glucose level above 126 mg/dL) * patients that signed the informed consent
Exclusion criteria
* patients with renal and hepatic disfunction, * patients with cardiac problems or other systemic alterations (allergies, pulmonary and gastrointestinal problems) * pregnant women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| blood glucose | 60 days | Blood glucose was measured using a Gluco Dr. Plus (AGM-3000) Blood Glucose Monitoring System. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Salivary glucose level | 60 days | The level of glucose in saliva was measured in laboratory after colleting non-stimulated saliva in test tubes. |
Countries
Brazil
Outcome results
None listed