Catheter Ablation, Persistent Atrial Fibrillation
Conditions
Keywords
atrial fibrillation, ablation catheter, left atrial appendage peak emptying velocity, tool for predicting successful catheter ablation
Brief summary
The purpose of this study was to determine whether left atrial appendage flow velocity, as determined using trans esophageal echocardiography (TEE), predicts the outcome after catheter ablation of persistent Atrial fibrillation( pAF).
Detailed description
40 PAF patients underwent 3D mapping and ablation. A stepwise approach including circumferential pulmonary vein (PV) isolation, continuous complex-fractionated electrogram (CFE) ablation and linear ablation was performed by the same operator. The procedural end point was termination of persistent AF by catheter ablation, either by conversion directly to sinus rhythm or to atrial tachycardia. Left atrial appendage (LAA) peak flow velocities were measured with transesophageal echography and averaged within each RR interval of 10 consecutive cardiac cycles.
Interventions
OTHERa complete transesophageal echocardiography
All patients were evaluated by a complete transesophageal echocardiography with multiplane probes with a 7-MHz transducer before catheter ablation .LA appendage flow was obtained by placing the pulsed Doppler sample volume at the orifice of the LA appendage, after which peak flow velocities were measured and averaged within each RR interval of 10 consecutive cardiac cycles
Sponsors
Clinique Pasteur
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Inclusion criteria
* First-time radiofrequency catheter ablation for pAF. pAF was defined as continuous AF lasting longer than 1 month, resistant to either electrical or pharmacological cardioversion. * Informed consent
Exclusion criteria
* Severe valvular disease requiring surgery * Valvular prosthesis * Known severe coronary artery disease * Atrial and/or ventricular thrombosis * New York Heart Association functional class III to IV * Cerebrovascular disease * Pulmonary embolism * Latent or manifest hyperthyroidism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| termination of persistent AF by catheter ablation | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrences of AF were therefore determined from holter monitoring at 3 and 6 months or 12 leads ECG in care of symptomatic palpitation with clinical interview. | — |
Countries
France
Outcome results
None listed