Skip to content

Chronic Pain Following Thoracic Surgery

Study of Persistent Postsurgical Pain Following Thoracic Surgery in Patients With Pulmonary Malignancies

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01144845
Acronym
PTPS-18
Enrollment
702
Registered
2010-06-16
Start date
2010-04-30
Completion date
2010-10-31
Last updated
2011-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Postoperative

Keywords

Thoracotomy, Thoracic Surgery, Thoracic Surgical Procedures, Thoracic Surgery, Video-Assisted, Lung Neoplasms, Thoracic Nerves

Brief summary

Pain that persists after the healing of a surgical wound has previously been described as an important, but often unrecognized clinical problem. Persistent postsurgical (chronic postoperative pain) is the consequence of either ongoing inflammation or more common neuropathic pain as a result of surgical damage to peripheral nerves. Previous studies have shown that chronic pain is a frequent and serious complication following thoracic surgery. However, the prevalence of chronic pain following both thoracoscopy and anterior thoracotomy in patients with pulmonary malignancies is poorly characterized and the impact of this pain on patients' lives remains unclear. Thus, this study aims to investigate the prevalence of chronic pain following thoracoscopy or anterior thoracotomy, and the severity and impact of persistent post-surgical pain on daily life. This study is working with several hypotheses: 1.) persistent postsurgical pain following lung cancer surgery is predominantly of neuropathic nature and the presence of neuropathic symptoms increases the severity of postsurgical pain and reduces the patient's quality of life, 2.) the prevalence of chronic pain is reduced over time, and 3.) less invasive thoracic surgical interventions reduces the risk of the development of chronic pain.

Interventions

PROCEDUREThoracic surgery

Thoracoscopy or anterior thoracotomy

Sponsors

University of Aarhus
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients who previously underwent thoracic surgery with lung resection from January 2000 to december 2009

Exclusion criteria

* Death

Design outcomes

Primary

MeasureTime frame
Presence of persistent postsurgical painWithin 10 years after thoracic surgery

Secondary

MeasureTime frame
Duration of postsurgical painWithin 10 years after thoracic surgery
Course of persistent postsurgical painWithin 10 years after thoracic surgery
Severity of postsurgical painWithin 10 years after thoracic surgery
Location of persistent postsurgical painWithin 10 years after thoracic surgery
Symptoms associated with persistent postsurgical painWithin 10 years after thoracic surgery
Treatment of and effect of treatment on persistent postsurgical painWithin 10 years after thoracic surgery
Effect of postsurgical pain on activity, mood, walking ability, work, interpersonal relations, sleep and quality of lifeWithin 10 years after thoracic surgery
Characteristics of persistent postsurgical painWithin 10 years after thoracic surgery

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026