Cigarette Smoking, Nicotine Dependence, Smoking Cessation, Tobacco Smoking
Conditions
Keywords
mindfulness, smoking, stress
Brief summary
The purpose of this study is to assess the effects of mindfulness training (MT) compared to standard Smoking Cessation Therapy (SCT) on smoking cessation and stress provocation in individuals trying to quit smoking.
Interventions
BEHAVIORALMindfulness Training
8 sessions of behavioral treatment for smoking cessation
BEHAVIORALSmoking Cessation Therapy
8 sessions of behavioral treatment for smoking cessation
Sponsors
Yale University
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
1. Between the ages of 18 and 60 2. Smoking 10 or more cigarettes per day 3. Fewer than 3 months of smoking abstinence in the past year 4. Motivated to stop smoking
Exclusion criteria
1. Current use of psychoactive medications that have not been at a stable dose for the past six months, are used as mood stabilizers, or are used as smoking cessation treatments. Individuals who are on psychoactive medications that are stable, not mood stabilizers, and not used for smoking cessations are excluded from fMRI sessions but not smoking cessation treatment. 2. Use of another investigational drug within 30 days 3. Any serious or unstable disease within 6 months 4. Meets criteria for substance dependence within the past year 5. Left handed (will be excluded from fMRI only)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Between group differences in continuous abstinence | during treatment and 6, 12 and 18 weeks after treatment initiation |
Secondary
| Measure | Time frame |
|---|---|
| Between group differences in perceived stress | 6, 12 and 18 weeks after treatment initiation |
Countries
United States
Outcome results
None listed