Effect Study of Optimized Intervention to Heroin Addicts

Barriers and Effect of Optimizing Intervention Protocols for Heroin Dependence in Community-based Methadone Maintenance Treatment (MMT): a Cohort Study

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01144390

Enrollment

240

Registered

2010-06-15

Start date

2010-04-30

Completion date

2011-06-30

Last updated

2011-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heroin Dependence

Keywords

heroin dependence, community-based, MMT

Brief summary

The purpose of this study is to explore barriers and determine whether optimizing protocol is effective in the treatment of heroin dependence in community-based MMT clinics.

Detailed description

Drug dependence is one of the most serious public health problems worldwide. In China, among more than 100, 0000 registered drug addicts mostly are heroin dependence. Drug dependence post great risks to physical condition, their family and society, and can lead to infectious disease transmission. Though almost 500 MMT clinics which can offer MMT service to heroin addicts have been set up, there are still some problems, for example, poor compliance, high rate of dropping out and relapse which affect the service delivery to them. The guideline developed by WHO focused on psychotherapy to opiate addicts with MMT. So delivery of a set of comprehensive, integrated psychotherapy to opiate addicts is very critical in such methadone clinics.

Interventions

BEHAVIORALcognitive behavioral therapy

cognitive behavioral therapy, one session per week and psycho-education lecture in group once per month

DRUGmethadone maintenance treatment

methadone maintenance treatment

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* clinical diagnosis of heroin dependence * must be able to take methadone

Exclusion criteria

* schizophrenia and mood disorder * physical disabilities who could not come to take part in psychotherapy sessions.

Design outcomes

Primary

Measure	Time frame	Description
treatment retention	12 months	retaining patients in the methadone maintenance treatment during and after the study.

Secondary

Measure	Time frame	Description
in-treatment performance.	12 months	treatment performance of addicts include: treatment sessions during the study, negative urine specimens, drop-out rate, severity of ASI,scores of HIV-related high risk sexual behavior, the temperature and character inventory, perceived stigma scale, self-esteem inventory,self efficacy, social support scores,drug use from self-report from baseline to 3 month and 6 month.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 4, 2026