Electromyographic (EMG) on the Anaesthesia Monitor

The Appearance of Electromyography on the Anaesthesia Monitor.

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01142635

Enrollment

Registered

2010-06-11

Start date

2009-04-30

Completion date

2010-03-31

Last updated

2010-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Keywords

Electroencephalogram, Electromyogram, Entropy Index, Bispectral Index, Neuromuscular blockade; rocuronium, Propofol, Intubation

Brief summary

Intubation may induce electromyographic (EMG) activity, causing depth of anaesthesia monitors to show misleadingly high values. The investigators want to investigate whether this EMG activity can be visually seen on the anaesthesia monitor.

Detailed description

Patients are anaesthetized with target controlled infusion of propofol. To facilitate intubation, the patients are randomized to receive rocuronium either 0,6 mg/kg or 1,2 mg/kg. BIS, Entropy and the biosignal collected with the Entropy strip are collected on a computer. The visible biosignal on the anaesthesia monitor is recorded with a video camera. BIS, Entropy, biosignal and video clip of the anaesthesia monitor will be analyzed in detail.

Interventions

DRUGRocuronium bromide

Rocuronium, iv, 0,6 mg/kg diluted with saline to double volume, bolus, single dose

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* females giving informed consent * age range 18-65 years * elective surgery: gynaecological * general anaesthesia * ASA classification 1 or 2

Exclusion criteria

* pregnancy * body mass index \> 30 * disease affecting CNS * overuse of alcohol * drug abuse * unability to understand, read or use Finnish language

Design outcomes

Primary

Measure	Time frame	Description
The behaviour of biosignal on the anaesthesia monitor	30 minutes	The visibility of elctromyogram and elctroencephalogram on the anaesthesia monitor

Secondary

Measure	Time frame	Description
The behaviour of depth of anaesthesia indexes (BIS, SE, RE) during intubation	30 min	Intubation-associated changes in the numerical values of BIS, SE, RE

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026