Analysis of Anti-inflammatory and Antioxidant Pathways in Lung Diseases by Haem Oxygenase-1 (HO-1) in Induced Sputum and Carbon Monoxide (CO) in Exhaled Air

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01140685

Enrollment

Registered

2010-06-09

Start date

2009-12-31

Completion date

Unknown

Last updated

2010-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Diseases

Keywords

mucus-stimulated (induced sputum), lung disease (asthma, COPD, ILD and OLD), HO-1 (heme oxigenase-1), oxidative stress, CO (carbon monoxide), The oxidative stress in lung diseases

Brief summary

This work will focus on the anti-inflammatory and antioxidant pathways in lung diseases by measuring HO-1 in induced sputum and CO in exhaled air in cases of four respiratory diseases, asthma, chronic obstructive pulmonary disease (COPD), occupational lung diseases (OLD) and interstitial lung disease (ILD).

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Male and female * Ages \>/= 18 years * Diagnosed with one or more lung diseases * Referred for sputum induction to the Pulmonary Laboratory in the Tel-Aviv Sourasky Medical Center

Design outcomes

Primary

Measure	Time frame
exhaled CO levels	2010-2011

Outcome results