Relative Efficacy of Vitamins D2 and D3 in Adult Humans

Vitamin D Status: Relative Efficacy of Vitamins D2 and D3

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01139840

Enrollment

Registered

2010-06-09

Start date

2010-01-31

Completion date

2010-09-30

Last updated

2011-10-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

vitamin D2, vitamin D3, ergocalciferol, cholecalciferol, vitamin D status, To determine relative potency of vitamins D2 and D3 under conditions of continuous administration, To determine change in vitamin D content of subcutaneous fat after 12 weeks' administration

Brief summary

Vitamin D2 in chronic dosing will produce less of an elevation of serum 25(OH)D than will the same dose of vitamin D3.

Interventions

DIETARY_SUPPLEMENTvitamin D2

Study Supplement

DIETARY_SUPPLEMENTvitamin D3

Study Supplement

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

21 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* willingness to withhold supplement use for duration of study * willingness to avoid sun exposure for duration of study

Exclusion criteria

* vitamin D supplement use * conditions that affect vitamin D metabolism by the body

Design outcomes

Primary

Measure	Time frame
AUC for increment in serum 25(OH)D	12 weeks

Secondary

Measure	Time frame
change in vitamin D content of subcutaneous fat	12 weeks

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026