Methicillin-Resistant Staphylococcus Aureus
Conditions
Keywords
Methicillin-Resistant Staphylococcus aureus, Decolonisation, Nursing homes, Infection Control
Brief summary
The purpose of this study is to determine the better approach between the currently procedure (i.e. standards precautions) and a reinforced strategy to control MRSA transmission in the institutionalized population of nursing homes in Canton of Vaud, Switzerland.
Detailed description
MRSA carriage among nursing homes residents of Canton Vaud, Switzerland, is increasing, despite use of standard precautions. Recommendation to prevent MRSA transmission in long term care facilities are lacking. We aim to reinforce the current infection control strategy by general MRSA screening of institutionalised residents and decolonisation of MRSA carriers. Because the uncertainties in the impact of this reinforced strategy, we aim to compare this action to the policy actually applied.
Interventions
OTHERintervention
5 days topical decolonisation including nasal mupirocin tid, chlorhexidine mouth wash tid, chlorhexidine body wash once daily. Daily direct resident's environmental disinfection during decolonisation.
Sponsors
University of Lausanne Hospitals
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* all nursing homes of canton Vaud, Switzerland, that give the consent of participation
Exclusion criteria
\- refusal to participate Inclusion criteria for decolonisation in intervention nursing homes: \- all MRSA positive residents living in a Nursing Home included in the intervention group
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To determine the change in prevalence of MRSA carriage among residents of each Nursing homes group at the end of the one study year | 1 year | in each control and intervention nursing home: MRSA screening of all residents of nursing homes of Canton Vaud, at baseline and 1 year later, in order to compare MRSA prevalence changes at nursing homes levels |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| To determine the effectiveness of the reinforced strategy to prevent MRSA infection, compared to the standard strategy | 1 year | In a subpopulation of all nursing homes residents (10% of the whole population), recording of all microbiologically documented MRSA infection, according to nosocomial infection definitions of the Center of Diseases Control (CDC) of Atlanta. |
Outcome results
None listed