Cognitive Symptoms, Traumatic Brain Injury
Conditions
Keywords
Rehabilitation Outcome, Cognitive treatment, TBI
Brief summary
The purpose of this study is to investigate the efficacy of a structured rehabilitation program on cognitive function and quality of life in individuals with blast-induced traumatic brain injury (bTBI).
Detailed description
The most common impairments following blast-induced traumatic brain injury (bTBI) are cognitive deficits in the domain of executive functioning, learning and memory, and functional and psychosocial disabilities that are closely related to these cognitive deficits. There are no treatment protocols available to address the multiple cognitive impairments in bTBI, but cognitive rehabilitation has proven efficacious in the treatment of non-blast TBI. The cognitive training modules the investigators plan to evaluate have improved organization and memory function in patients with non-blast TBI, but it is unknown whether their efficacy exceeds that of programs that focus only on education and support. This study is a between group comparison of a cognitive rehabilitation treatment designed specifically to address the most common cognitive complaints in executive and memory function, and an active control group receiving educational intervention geared at personal management of TBI-related symptoms.
Interventions
BEHAVIORALCognitive Intervention
Cognitive rehabilitation treatment designed specifically to address the most common cognitive complaints in executive and memory function
BEHAVIORALEducational intervention
Educational intervention is geared at personal management of TBI-related symptoms.
Sponsors
VA Office of Research and Development
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
21 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF) active-duty personnel or Veterans exposed to blast * Meets criteria for mild TBI * loss of consciousness (LOC) of 30 min or less * Age: 21- 50
Exclusion criteria
* Evidence of penetrating head injury * History of previous neurological diagnosis * History of previous psychotic disorder prior to the blast exposure * Hearing or vision impairment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cognitive functioning | Ten weeks | Scaled Score on the standardized neuropsychological testing |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Daily functioning | Ten weeks | Total Score on the daily functioning measure |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORYelena Bogdanova, PhD PhD
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
Outcome results
None listed