Fragmented QRS, MACE, Primary PCI
Conditions
Brief summary
To investigate the prognostic significance of a fragmented QRS (fQRS) complex in a patient who had undergone primary percutaneous coronary intervention (PCI).
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients with chest pain that continued longer than 30 minutes and with ≥ 2 mm ST elevation in ECG at least in two adjacent derivations were diagnosed with an acute STEMI. In all patients, at least two-fold increases were seen in serum CK-MB levels compared to normal values.Having acute STEMI for the first time was stipulated for inclusion in the study.
Exclusion criteria
* Subjects with known allergies to aspirin and clopidogrel, inadequate echocardiographic images, malignancy, a previous cerebrovascular event, renal dysfunction (creatine level \> 2.5 mg/dl), a previous MI, or a history of cardiogenic shock as well as those who refused to participate in the study were excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Major Adverse Cardiac Events | — | the presence of a fQRS at 48 hours after primary PCI is a significant parameter in predicting adverse cardiovascular events; |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Q Wave and QRS distortion for predicting major adverse cardiac events | — | the presence of a fQRS is a more sensitive and specific parameter in predicting development of adverse cardiovascular events than Q wave and QRS distortion; and compared to Q wave, fQRS correlated more significantly with the presence of a scar |
Countries
Turkey (Türkiye)