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Resistance Training in Patients With Chronic Obstructive Lung Disease (COPD): Whole Body Vibration Versus Conventional Resistance Training

Resistance Training in Patients With Chronic Obstructive Lung Disease (COPD): Whole Body Vibration Versus Conventional Resistance Training

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01135966
Acronym
REWORK
Enrollment
62
Registered
2010-06-03
Start date
2010-04-30
Completion date
2011-11-30
Last updated
2011-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD

Keywords

COPD, Whole Body Vibration training, Conventional resistance training

Brief summary

Pulmonary rehabilitation has been emerged as a recommended standard of care for patients with chronic lung disease based on a growing body of scientific evidence. A set of evidence-based guidelines were published in American College of Chest Physicians (ACCP) and the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR). Since then, the published literature in pulmonary rehabilitation has increased substantially, and other societies have published important statements about pulmonary rehabilitation (eg, the American Thoracic Society and the European Respiratory Society). In patients with COPD, there is a strong scientific basis for implementing conventional resistance training (CRT) in addition to endurance training. Endurance training, such as walking, is a key component of pulmonary rehabilitation and improves in exercise tolerance and muscular endurance. However, this type of training may not reverse muscle weakness or atrophy. For that reason, strength training seems to be the optimum training modality to increase muscle mass and strength. Recently, Whole-Body-Vibration (WBV) training has been promoted as an alternative for resistance training on multigym equipment. In WBV training, the subject stands on a platform that generates vertical sinusoidal vibration, during which static and dynamic exercises can be performed. The present study is conducted to provide an answer on the following question: will a resistance training program, such as the whole body vibration, be even effective than a conventional resistance training program in patients with COPD.

Interventions

BEHAVIORALConventional resistance training program

Conventional resistance training program is followed.

BEHAVIORALWhole body vibration resistance training program

WBV training on FITVIBE

Sponsors

University Hospital, Ghent
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Patients with COPD candidate for pulmonary rehabilitation * Men and female between 40 and 80 years of age * Written informed consent to participate

Exclusion criteria

* Severe cardiac, neurological and orthopedic co-morbidity interfering with exercise training. * Pacemaker * Hip, knee of shoulder prosthesis or recently introduced spirals, metal pens, bolts or plates * Uncontrolled diabetes, epilepsy or migraine * Osteoporotic or metastatic fractures, acute hernia, discopathy, spondylitis

Design outcomes

Primary

MeasureTime frameDescription
estimation of the change of 6 MWD before and after 12 weeks resistance training program (CRT versus WBV training)before and after 12 weeksestimation of the change of 6 MWD (submaximal walking test)after a 12 week conventional resistance training program or after a 12 week whole body vibration training program

Secondary

MeasureTime frameDescription
changes in body composition after CRT or after WBV training in patients with COPDbefore and after 12 weeksmeasured by bioelectrical impedance analysis: Fat Free Mass (FFM)before and after 12 weeks of training.
changes in maximal exercise capacity after CRT or after WBV training in patients with COPDbefore and after 12 weeksmeasured by cyclo-ergospirometry before and after 12 weeks of training
changes in muscle force after CRT or after WBV training in patients with COPDbefore and after 12 weeksmeasured by handgrip force, maximal inspiratory pressure (PImax) and maximal expiratory pressure (PEmax)before and after 12 weeks of training
changes in muscle strength (quadriceps force)after CRT or after WBV training in patients with COPDbefore and after 12 weeksmeasured by modified Microfet before and after 12 weeks of training.
changes in Dyspnea scores after CRT or after WBV training in patients with COPDbefore and after 12 weeksmeasured by Chronic Respiratory Disease Questionnaire domain dyspnea (CRDQd) and by the BORG scale before and after 12 weeks of training.
changes in 6MWD and the endurance test on the bicycle after CRT or after WBV training in patients with COPDbefore and after 12 weeksmeasured by endurance test on the bicycle (75% Max. Workload)before and after 12 weeks of training. This test will also be repeated after 6 weeks of training.
changes in Quality of life after CRT or after WBV training in patients with COPDbeforer and after 12 weeksmeasured by CRDQ (Chronic Respiratory Disease Questionnaire)before and after 12 weeks of training

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026