Astigmatism, Hyperopia, Myopia
Conditions
Keywords
Myopia, Hyperopia, Astigmatism, PRK, LASIK
Brief summary
Subjects with myopia, hyperopia and astigmatism are being randomized to be treated in one eye with a wavefront-guided excimer laser and their fellow eye treated with a wavefront-optimized excimer laser.
Detailed description
Subjects with myopia, hyperopia and astigmatism are being randomized by ocular dominance to be treated with either PRK or LASIK. One eye will be treated with a wavefront-guided excimer laser and the fellow eye will be treated with a wavefront optimized excimer laser.
Interventions
PROCEDURELASIK and PRK
Wavefront-guided versus wavefront-optimized LASIK or PRK.
Sponsors
Edward E. Manche
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy subjects age 21 and older. * Subjects with nearsightedness, farsightedness and/or astigmatism.
Exclusion criteria
Autoimmune diseases. * Children. * Women pregnant or nursing. * Ectatic corneal disease. * Previous ocular surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in best spectacle corrected visual acuity. | One year |
| Changes in 25 and 5% low contrast visual acuity. | One year |
| Improvement in uncorrected visual acuity | One year |
Secondary
| Measure | Time frame |
|---|---|
| Changes in higher order aberrations. | One year |
| Topographic changes. | One year |
| Quality of vision changes. | One year |
Countries
United States
Outcome results
None listed