Cytokine Assay for Early Identification of Pediatric Stem Cell Transplant Recipients

Cytokine Assay for Early Identification of Pediatric Stem Cell Transplant Recipients at Risk for Respiratory Failure

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01135355

Enrollment

Registered

2010-06-02

Start date

2008-07-31

Completion date

2011-01-31

Last updated

2024-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Stem Cell Transplant Failure

Brief summary

The aim of our study is to determine whether a clinically relevant laboratory measurement (of seven specific immunologic biochemicals in the blood) can identify which bone marrow transplant recipients are likely to progress to respiratory failure. Our ultimate goal is to devise a comprehensive and inclusive laboratory test that is effective at determining who is likely to go on to respiratory failure, in order to facilitate early medical intervention.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 21 Years

Healthy volunteers

Inclusion criteria

- Hematopoietic stem cell transplantation (HSCT) for any indication. * Patients will range from age 0 to age 21. There is no gender restriction. We expect the male to female ratio to end up being about 50/50 * Ability to understand and the willingness to sign a written informed consent document.

Design outcomes

Primary

Measure	Time frame
Compute median flourescence intensity, standard curves, and estimated pg/mL for each cytokine.	weekly during hospitalization for transplant

Countries

United States

Outcome results