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The Impact of Thumb Carpometacarpal Osteoarthritis on General Health

The Impact of Thumb Carpometacarpal Osteoarthritis on General Health

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01133197
Enrollment
188
Registered
2010-05-28
Start date
2009-07-31
Completion date
2015-06-30
Last updated
2015-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thumb Arthritis

Keywords

thumb, arthritis, Impact of thumb arthritis on health

Brief summary

This study is designed to define the impact of thumb arthritis on patient's general health. As a secondary objective, data will be analyzed to determine the effects of medical and musculoskeletal comorbidities on the rating of upper extremity function by the patient.

Detailed description

This study is designed to define the impact of thumb arthritis on patient's general health. As a secondary objective, data will be analyzed to determine the effects of medical and musculoskeletal comorbidities on the rating of upper extremity function by the patient. Potential Contribution: The data that we intend to gather could further our understanding of the overall health impact of thumb osteoarthritis and allow surgeons to more accurately interpret patient-rated measures of upper extremity function in the presence of comorbidities. Osteoarthritis of the thumb carpometacarpal joint is one of the most common sites of arthritic degeneration in the hand. To date, no study has examined this conditions impact on overall health using a validated health measure (e.g. SF-36). Additionally, no study has examined the impact of medical and musculoskeletal comorbidities on patient-rated measures of upper extremity function in these patients.

Interventions

None listed

Sponsors

University of Rochester
CollaboratorOTHER
Washington University School of Medicine
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Healthy adults clinically diagnosed with thumb carpometacarpal osteoarthritis. The diagnosis must have been confirmed radiographically prior to consideration for study enrollment. * Adults accompanying patients to participating offices will be recruited to be control subjects. They must not be receiving medical or surgical treatment for a hand or wrist complaint. * Additionally control subjects must not have been diagnosed with thumb osteoarthritis.

Exclusion criteria

* Subjects must be over 18 years of age and English speaking. * Subjects are not to include incarcerated adults or those unable to provide consent for study participation. * Patients diagnosed with currently symptomatic hand or wrist pathology outside of the thumb carpometacarpal joint will be excluded. * Patient with prior surgery on the affected thumb will be excluded. * Pregnant females are excluded from study participation with pregnancy determined by patient self-reporting (standard of care before office radiographs).

Design outcomes

Primary

MeasureTime frameDescription
Hand FunctionBaselineUse of hand by Michigan Hand Questionnaire

Secondary

MeasureTime frameDescription
Overall HealthBaselineSF-36

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026