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Malnutrition and Outcome in Hospitalized Children in Europe

Malnutrition and Outcome in Hospitalized Children in Europe (ESPEN Network Grant Project)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01132742
Enrollment
2567
Registered
2010-05-28
Start date
2010-02-28
Completion date
2012-12-31
Last updated
2013-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition

Keywords

Malnutrition, children, Hospital Stay, Screening Tools, Anthropometry

Brief summary

Malnutrition in children has even more severe consequences on disease course and long-term health than malnutrition in adults. According to prior studies, malnutrition affects about 15-30 % of hospitalized children in Europe (ESPGHAN 2005, Pawellek et al 2008, Joosten and Hulst 2008). However, available criteria for defining malnutrition in paediatric patients are inconsistent, not based on firm evidence, and not generally agreed upon. Current guidelines do not address assessment of and screening for childhood malnutrition. Therefore, a large number of affected children are not adequately diagnosed. One aim of this study is to assess the prevalence of malnutrition and patients at risk for malnutrition among at least 2700 hospitalized children mainly across Europe. In addition criteria to link anthropometric measurements and the prediction of outcome, i.e. length of hospital stay, shall be established. A further goal then is to establish agreed, evidence-based criteria for malnutrition in children with the purpose of leading to an agreed, evidence-based screening tool for paediatric malnutrition in developed countries. This tool shall include a set of simple questions, based on previously suggested tools. Thereby this study will provide a strong basis for implementing evidence-based nutritional interventions in paediatric patients by harmonisation of diagnostic criteria for childhood malnutrition in developed countries.

Interventions

None listed

Sponsors

Ludwig-Maximilians - University of Munich
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Months to 18 Years
Healthy volunteers
No

Inclusion criteria

* Children admitted to the participating hospitals during the study period * Age between 1 month and 18 years * Expected hospital stay exceeding 24 hours * Parents/caregivers, as well as those patients capable to comprehend, agree to participation and sign the informed consent form

Exclusion criteria

* Infants with premature birth (\<37 weeks gestational age) during the first 12 months of life * Infants \< 1 month of age * Patients ≥ 18 years of age * Children in need of intensive care * Children admitted to day-care (LOS \< 24hours) * Patients admitted for elective reasons with an expected hospital stay \<24 hours

Design outcomes

Primary

MeasureTime frameDescription
Length of Hospital Stay60 daysLength of Hospital Stay will be compared between malnourished and non malnourished children.

Secondary

MeasureTime frameDescription
infection as a complication during hospital stay60 daysfrequency of infectious complications (number of days with temperature \>38,5°C, number of days with days with antibiotic use)
gastrointestinal complications (vomiting, diarrhoea)60 daysfrequency of gastrointestinal complications: frequency of vomiting and diarrhoea during hospital stay
muscle strengthwithin 24 hours after admissionmaximal isometric grip force in children ≥ 6 years of age measured within 24 hours after admission

Countries

Croatia, Denmark, France, Germany, Greece, Israel, Italy, Netherlands, Poland, Romania, United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 21, 2026