Dysphagia
Conditions
Keywords
swallowing, stroke
Brief summary
The purpose of the research study is to investigate the effect of a brain stimulation technique called Transcranial Direct Current Stimulation (TDCS) in improving swallowing functions in subjects who develop dysphagia after a unilateral hemispheric infarction.
Interventions
OTHERtDCS
tDCS will lead to an increase in cortical excitability
OTHERSham
Sham will provide identical subjective sensation as tDCS
Sponsors
Beth Israel Deaconess Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Acute ischemic stroke * Between 24-168 hours after onset * Moderate to severe dysphagia based on swallowing assessment
Exclusion criteria
* Preexisting swallowing impairment * Intracerebral hemorrhage * Pacemaker of other electrically sensitive device
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Dysphagia Outcome and Severity Scale Score (DOSS) | 5 days after study enrollment | DOSS is a validated swallowing assessment scoring system that will rate the severity of dysphagia. It will be performed by a speech and swallow pathologist. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of seizure | 5 days after study enrollment | Number of patient having seizures during the 5 sessions of stimulation in either groups will be tabulated and compared. |
Countries
United States
Outcome results
None listed