Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope

Control of Acute Variceal Bleeding Using the Multi-shooter Band Ligator Compared to Injection Sclerotherapy.

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01131962

Enrollment

200

Registered

2010-05-27

Start date

2008-05-31

Completion date

2012-07-31

Last updated

2014-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematemesis, Portal Hypertension

Keywords

esophageal varices, hematemesis, endoscopy

Brief summary

Band ligation and injection sclerotherapy are two modalities of treatment that are applied using the endoscope. The purpose of this study is to determine which of two methods is better for controlling bleeding from the upper gut.

Detailed description

The use of band ligation for endoscopy during the attack of hematemesis is a novel practice as opposed to injection sclerotherapy.

Interventions

PROCEDUREEndoscopic control of hematemesis

Endoscopy is performed to diagnose the cause of hematemesis and to control it using band ligation or sclerotherapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Active hematemesis * esophageal varices

Exclusion criteria

* Hemodynamic unstability * Hepatic coma or precoma * Tense ascitis * Coagulopathies * concomitant gastric varices

Design outcomes

Primary

Measure	Time frame	Description
control of hematemesis	72 hours	Success for either techniques to be able to stop the bleeding promptly and maintain that for 72 hours

Secondary

Measure	Time frame	Description
occurence of complications from the intervention	30 days	the study subjects are reveiwed in 30 days to detect any complications secondary to the endoscopic intervention.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026