Establishment and Characterization of Patient-Derived Non-Small Cell Lung Cancer Xenografts and Cell Cultures

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01130571

Enrollment

Unknown

Registered

2010-05-26

Start date

2011-09-30

Completion date

2014-12-31

Last updated

2014-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non Small Cell Lung Cancer

Brief summary

Xenografts and cell cultures provide sufficient material for analyses at the protein, RNA and DNA level. Patient derived NSCLC xenografts and cell lines are available but none however are Asian in origin. Given the emerging evidence to suggest inter-ethnic differences in NSCLC biology, new models of preclinical drug evaluation should be designed and validated using Asian tumors. Furthermore, such models will allow studies of biological mechanisms of sensitivity and/or resistance and also the study of dynamic regulations under standardized conditions in the Asian context.

Interventions

PROCEDUREXenografts and cell cultures

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients aged 21 years and above. * Undergoing a surgical resection of tumor as part of clinical management

Exclusion criteria

* Patient or legally acceptable representative unable to provide consent patient in the judgement of the study investigator, is medically unsuitable for this study

Countries

Singapore

Contacts

Primary ContactRoss Andrew Soo, MBBS

ross_soo@nuhs.edu.sg65 3772 4624

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026