The Effect of DHEA on Markers of Ovarian Reserve in Women With Diminished Ovarian Reserve

Status

Terminated

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01129830

Enrollment

200

Registered

2010-05-25

Start date

2010-01-31

Completion date

2014-09-30

Last updated

2014-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

ovarian reserve, FSH, anti-mullerian hormone, estradiol, oocyte, IVF, embryo transfer

Brief summary

This prospective study evaluates the effect of DHEA supplementation on markers of ovarian reserve in women with diminished ovarian reserve.

Detailed description

Ovarian reserve markers, such as FSH, estradiol, AMH, ovarian volume and antral follicle counts will be monitored on DHEA supplementation in a prospective fashion.

Interventions

DIETARY_SUPPLEMENTdehydroepiandrosterone

DHEA supplementation 25 mg tid for 3 months

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

21 Years to 44 Years

Healthy volunteers

Inclusion criteria

* infertile women with diminished ovarian reserve

Exclusion criteria

* women \> 45

Design outcomes

Primary

Measure	Time frame	Description
live birth rate	3 years	Live birth rate will be monitored for women who took DHEA supplementation

Secondary

Measure	Time frame	Description
number of oocytes	3 years	Number of retrieved oocytes for patients undergoing IVF will be monitored along with ovarian response

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026