Renal Artery Stenosis, Hypertension
Conditions
Keywords
Fractional flow reserve, Revascularization, Prognosis, Hemodynamics, Hypertension
Brief summary
The purpose of the study is to determine potential utility of renal fractional flow reserve in prognosis predicting after renal stent implantation.
Interventions
PROCEDURERenal artery stenting
Sponsors
Ministry of Science and Higher Education, Poland
National Institute of Cardiology, Warsaw, Poland
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* At least moderate (60% or more) renal artery stenosis with atheromatic appearance in angiography * Hypertension defined according to WHO criteria * Age 18-75 years * Signed informed consent obtained
Exclusion criteria
* Bilateral renal artery stenosis or significant renal artery stenosis in solitary kidney * Contraindications to percutaneous renal angioplasty with stenting * Atrophy of the kidney supplied with stenosed artery * Other well known secondary reason for hypertension * Chronic heart failure NYHA II-IV * Significant valvular heart disease qualified for surgery * Persistent atrial fibrillation * Renal failure with GFR below 30ml/min
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure improvement | 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Kidney function preservation | 6 months |
Countries
Poland
Outcome results
None listed