Indicators of Inflammation and Coagulation in Sepsis

Temporal Behavior of Coagulation Factors, Cytokines and Tissue Injury Markers in Sepsis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01128283

Enrollment

500

Registered

2010-05-21

Start date

2002-01-31

Completion date

2014-05-31

Last updated

2014-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Keywords

Sepsis, organ failure, cytokines, clotting factors

Brief summary

We will collect blood samples from patients with the diagnosis of sepsis and other ICU patients. We will describe the course of different mediator levels and organ injury markers and follow their progression throughout the course of the study.

Detailed description

After informed consent is obtained 5 cc of blood is collected on the day of admission and on days 0, 1, 3, and 7 thereafter. Plasma is collected and frozen for the subsequent measurement of biomarkers.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Admission to the ICU

Exclusion criteria

* No blood draws scheduled * Hemoglobin level \< 6,5 gm/dl

Design outcomes

Primary

Measure	Time frame	Description
Death	30 days	Survival at 30 days

Countries

United States

Outcome results