Diabetic Gastroparesis, Gastroesophageal Reflux Disease
Conditions
Keywords
Metoclopramide, Randomized Controlled Trial
Brief summary
The investigators hypothesized that: 1\) an intervention targeted at the prescribing physician would increase the rate of a metoclopramide discontinuation among patients prescribed the medication for questionable or unclear indications; and 2) the discontinuation would be durable.
Interventions
OTHERintervention letter
Physicians in the intervention group were mailed a written feedback letter regarding their patients who were prescribed questionable metoclopramide therapy. Non-intervention providers received no letter. The letter consisted of the following components: 1. The name and medical record # of the patients involved 2. Information regarding the metoclopramide prescription: dates, dosage, indication recorded, and the duration of therapy 3. A reminder of the adverse effect of long-term metoclopramide therapy 4. A recommendation to consider having the patient undergo a trial of metoclopramide discontinuation if appropriate, and documentation of a discussion of risk and benefits of metoclopramide therapy with patients 5. A request that the physician document the discontinuation trial in the electronic medical record
Sponsors
University of Pennsylvania
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Physicians at University of Pennsylvania Health System who ordered an active metoclopramide prescription with a questionable indication.
Exclusion criteria
* Physicians-in-training (e.g., residents, fellows) * Physicians how were investigators on this study * Physicians serving on the the University of Pennsylvania Drug Use and Effects Committee or Information Technology Oversight Board
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Discontinuation of metoclopramide therapy | 12 weeks after intervention period | Twelve weeks after the intervention period, we searched the medical records of patients in the intervention and non-intervention groups to determine whether discontinuation of metoclopramide therapy had taken place. |
Countries
United States
Outcome results
None listed