A Double Blind Crossover Study on the Effect of Methylphenidate on Decision-making Ability of Adults With ADHD Compared to Healthy Adults

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01124032

Enrollment

Registered

2010-05-14

Start date

2010-05-31

Completion date

Unknown

Last updated

2010-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ADHD

Brief summary

The study assesses the effect of Ritalin on working memory,attention,and decision-making measures in adults with ADHD and compares it to its effect on healthy adults, in a double-blind crossover design.We hypothesize that Ritalin will result in better performance in all measures,and that the improvement will be greater in the ADHD group.

Interventions

DRUGmethylphenidate

a capsule containing 20 mg

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

21 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* adults in the age of 21-50

Exclusion criteria

1. People diagnosed with a clinical disorder other than ADD/ADHD that may impair their performance in the tasks used in the study. 2. People for whom there is a contra-indication for consuming Ritalin. 3. Pregnant women and nursing women;

Design outcomes

Primary

Measure	Time frame
TOVA score	assessed twice, separated by 1-2 weeks.
IGT score	assessed twice, separated by 1-2 weeks
FPGT score	assessed twice, separated by 1-2 weeks
SWM score	assessed twice, separated by 1-2- weeks
digit span score	assessed twice, separated by 1-2- weeks

Countries

Israel

Contacts

Primary ContactZiv Carmel, MD

zivca@clalit.org.il97297478570

Backup ContactNirit Agay, Msc

niritag@clalit.org.il97297478644

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026