Aging, Fracture, Osteoporosis
Conditions
Keywords
osteoporosis, fracture risk, aging, tibia, sonometer, ultrasound, BMD, bone mineral density, DXA, 3D-HRpQT, waveform profiles
Brief summary
Study to demonstrate that the Bone UltraSonic Scanner (BUSS) can aid in detection of osteoporosis and predict prevalent osteoporotic fractures. Measurements derived from the BUSS parameters will be able to discriminate between postmenopausal women with osteoporotic fractures when compared to matched controls without history of osteoporotic fracture.
Detailed description
One of several studies to develop and clinically validate a novel ultrasonographic device, BUSS, for the assessment of osteoporosis and fracture risk.
Interventions
None listed
Sponsors
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Mayo Clinic
Artann Laboratories
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* postmenopausal women with osteoporotic fracture at spine or wrist * postmenopausal women no history of fracture at spine or wrist
Exclusion criteria
* women with a history of metabolic disease * stroke * tibia fracture or surgery * BMI ≥ 35 kg/m2 * Teriparatide use currently or within the past 6 months, * Any skin issues (open wounds or rashes, and/or skin infections) of the tibial area.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determine whether BUSS testing is equivalent or superior to DXA for fracture risk assessment in postmenopausal women. | 1 year |
Countries
United States
Outcome results
None listed