Multiple Sclerosis
Conditions
Keywords
Multiple Sclerosis, b1b-interferon, Fatigue, Exercise
Brief summary
The purpose of this study is to investigate the effects and tolerability of exercise on side effects of injectable disease modifying treatments in multiple sclerosis. The investigators main hypothesis is that controlled exercise is safe and can be well tolerated in patients with multiple sclerosis and it can improve disease modifying treatment related side effects such as fatigue.
Detailed description
Patient compliance with disease modifying treatment largely depends on relatively common side effects of such treatments such as fatigue. Regular exercise can potentially improve these side effects. However, Safety and effects of exercise has not been studied in patients with multiple sclerosis. Our main aim is to study the safety, tolerability and effects of exercise on side effects of subcutaneous interferon-b1b in patients with Multiple Sclerosis.
Interventions
Two 2-hours long interactive training to perform safe and efficient aerobic exercise for patients with multiple sclerosis
Sponsors
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma
University of British Columbia
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Recent diagnosis of relapsing remitting multiple sclerosis on treatment with b1b-interferon disease modifying treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Multiple Sclerosis Fatigue | — |
| Quality of Life | — |
| Injection site visual analog scale (0-10) | — |
Countries
Canada
Outcome results
None listed