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The Effect of Gabapentin (Neurentin) and Pregabalin (Lyrica) in Pain Reduction After Photorefractive Keratectomy

Status
UNKNOWN
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01122004
Acronym
PRK
Enrollment
Unknown
Registered
2010-05-12
Start date
Unknown
Completion date
Unknown
Last updated
2010-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractive Errors

Brief summary

The studied patients will be given randomly one of three following drugs1:Gabapentin2: Pregabalin or placebo for 3 days after Photorefractive keratectomy surgery. The pain will be measured based on visual analog scale(VAS) on the day of operation and on the 3 rd day (morning, evening) and then compared among three groups.

Interventions

DRUGPregabalin

Sponsors

Shahid Beheshti University of Medical Sciences
Lead SponsorOTHER

Study design

Primary purpose
TREATMENT

Eligibility

Sex/Gender
ALL
Age
17 Years to No maximum

Inclusion criteria

* patients candidate for PRK, 17\<age\<70

Exclusion criteria

* use of any systemic analgesic drugs, drug intolerance, need of systemic or topical administration of NSAIDs or eye drops for allergy and glaucoma, dry eyes, pregnancy, breast feeding

Design outcomes

Primary

MeasureTime frame
pain degree based on visual analog scale(VAS)—

Countries

Iran

Contacts

Primary ContactAmir faramarzi, MD
+982122585952

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026