Fluid Resuscitation With HES 200/0.5 10% in Severe Burn Injury

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01120730

Enrollment

Registered

2010-05-11

Start date

1997-04-30

Completion date

2009-03-31

Last updated

2010-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Failure, Survival

Brief summary

HES 200/0.5 10% is equal to ringers lactat solution.

Detailed description

30 Patients were enrolled to the study, either to the hyperoncotic HES 200/0.5 (10%) group or to the crystalloids only group. After a treatment protocol of 72 hours we collected data about complications like pulmonary failure and abdominal compartment syndrome. Furthermore, we addressed the question of incidence of mortality and renal failure.

Interventions

DRUGfluid resuscitation

fluid resuscitation with HES

DRUGFluid resuscitation

Fluid resuscitation in standardized fashion

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* All burn victims with burned surface area bigger than 20%

Exclusion criteria

* Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Intensive care unit mortality	28 days	28 days

Secondary

Measure	Time frame	Description
fluid amount during the first 72 hours	28 days	Fluid resuscitation after burn

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 31, 2026