Prevalence of Malnutrition in Oncologic Patients

Prevalence and Impact of Malnutrition in Hospitalised Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01120483

Enrollment

400

Registered

2010-05-11

Start date

2006-12-31

Completion date

2007-06-30

Last updated

2010-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer, Malnutrition

Keywords

mortality, functional status

Brief summary

Malnutrition is a common phenomenon in cancer patients. Deteriorated nutritional status is associated with poor clinical outcome. The purpose of this study is to determine the prevalence of hospital malnutrition and its impact on functionality, quality of life and mortality in cancer patients and to test the reference percentiles of phase angle values (Bosy Westphal et al JPEN 2006) as indicator of cancer cachexia and predictor of mortality. Hypothesis: The fifth reference percentile of the phase angle norm values is a prognostically relevant cut off value indicating cancer cachexia in terms of malnutrition, fatigue and impaired functional status, as well as predictive of 6-month mortality

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients suffering from cancer. * Patients who have signed a written Informed Consent.

Exclusion criteria

* Patients with implanted pacemaker or defibrillator * Patients with neuromuscular disease or hemiplegia.

Design outcomes

Primary

Measure	Time frame	Description
Prevalence of malnutrition	1 day	Phase angle (bioelectrical impedance analysis) Nutritional status(SGA), muscle function (grip strength)

Secondary

Measure	Time frame	Description
Quality of life	1 day	Quality of life is determined with the questionnaire QLQ C-30 of the European Organisation for Research and Treatment of Cancer (EORTC)
Mortality	6 months	Patients are going to be contacted via telephone six months after the first assessment. Deceased patients will be determined by the local death register
Depression	1 day	Risk for depression is assessed using the Center for Epidemiological Studies Depression Scale (CES-D)

Countries

Germany

Outcome results