Adherence, HIV, HIV Infections, Sexual Behavior
Conditions
Keywords
Adherence, Appointment, Cell Phone, Cellular Phone, Clinic, Computers, Controlled Clinical Trials, Randomized, HIV/AIDS, Health Informatics, Health behavior, Information Technology, Internet, Intervention, Medication, Patient Satisfaction, Patient Self-Report, Patients, Peru, Phone, Public Health, Public Health Informatics, Randomized, Randomized Controlled Clinical Trials, Randomized Controlled Trials, Research, Secondary Prevention, Self-Report, Sex Behavior, Sexual Behavior, Sexually Transmitted Diseases, Sexually Transmitted Infection, Survey Instrument, Surveys, Telephone, Telephone, Cellular, Text, Unprotected Sex, Viral Load result, Vulnerable Populations, WWW, anti-retroviral therapy, consumer informatics, evidence base, follow-up, medication adherence, medication compliance, randomization, randomized controlled study, randomized trial, randomly assigned, safer sex, treatment adherence, user centered design, web, world wide web
Brief summary
The investigators propose to develop and evaluate a computer-based intervention using cell phones to enhance adherence to antiretroviral treatment (ART) and support of HIV transmission risk-reduction among adult HIV-positive patients in Peru.
Detailed description
Adherence to ART is critical for treatment success at the individual level and to avoid the onset of resistant strains of HIV. In Peru, where ART has recently been introduced, adherence to HIV treatment has not yet been addressed properly. Innovative approaches using information technologies such as cell phones are needed to increase adherence to ART for people with HIV/AIDS. The specific aims of the study are to: 1) Conduct formative research to assess culturally-specific behavioral messages to be included in the computer-based system; 2) Develop and test an interactive computer-based system using cell phones to enhance adherence to ART and to deliver HIV transmission risk reduction messages; 3) Evaluate the impact of the system on antiretroviral adherence and sexual risk behaviors.
Interventions
Participant receives short text messages, including: antiretroviral reminders, clinic appointment reminders, and preventive/educational messages
Sponsors
Fogarty International Center of the National Institute of Health
Universidad Peruana Cayetano Heredia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* HIV-positive healthy male or female aged greater than or equal to 18 * Currently on ART * Patients with a mobile phone for their personal use (not shared) * Patients who know how to retrieve read text messages on their mobile phone * Signed and dated written informed consent prior to admission to the study
Exclusion criteria
* Patients whose clinical condition might have interfered with the study (e.g., deafness, serious mental illness, mental retardation) * Patients unable to give their informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Self-reported medication adherence | 12 months |
| HIV-1 viral load | 12 months |
Secondary
| Measure | Time frame |
|---|---|
| CD4 | 12 months |
| Self-reported HIV transmission risk behaviors | 12 months |
Countries
Peru
Outcome results
None listed