Seizures Post Intracerebral Hemorrhage

Are Post Intracerebal Hemorrhage Prevented By Anti-Epileptic Treatment?

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01115959

Enrollment

Registered

2010-05-04

Start date

2003-02-28

Completion date

2008-12-31

Last updated

2014-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Cerebral Hemorrhage

Brief summary

This study examines early antiepileptic treatment with valproic acid for acute cerebral hemorrhage against a placebo group immediately post event to evaluate the outcome of these patients regarding seizures and neurological outcome.

Interventions

DRUGvalproic acid

treatment of 1 month dosage of 400 mg BID

DRUGplacebo bid

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* cerebral hemorrhage spontaneous

Exclusion criteria

* early seizures

Design outcomes

Primary

Measure	Time frame
number of seizures	study drug for 1 month and 1 year follow up

Secondary

Measure	Time frame
neurological outcome NIHSS	during 1 month study drug and 1 year post follow up

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026