SPECT/CT in the Diagnosis of Dementia

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01112501

Acronym

DEMSPET

Enrollment

Registered

2010-04-28

Start date

2006-09-30

Completion date

2010-01-31

Last updated

2010-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementia

Keywords

Diagnosis, Dementia, Imaging

Brief summary

Aim of the study is to evaluate whether Tc-99m-ECD-SPECT/CT enhances early diagnosis of dementia in two specific patient groups: (1) patient with mild cognitive impairment, and (2) patient with possible symptoms and signs of frontotemporal dementia. Evaluation of SPECT/CT data is performed both by visual and quantitative voxel-based analyses (Statistical Parametric Mapping). The final diagnosis is based on up to four years clinical follow-up.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

(one of these): * healthy control * mild cognitive impairment (recruited from a population based data) * clinically suspected frontotemporal dementia (unset diagnosis)

Exclusion criteria

* unable to be scanned with SPECT/CT

Design outcomes

Primary

Measure	Time frame	Description
Final diagnosis	4 years	(1) controls, (2) stable mild cognitive impairment (MCI), (3)MCI converted to Alzheimers's disease (AD), (4) frontotemporal dementia (FTD), suspected FTD converted to AD, (5) other final diagnoses

Countries

Finland

Outcome results