Morbid Obesity
Conditions
Brief summary
This study will assess various published staging tools to assess the health impacts of obesity on individuals. The aim is to identify benefits and drawbacks, and thus help Obesity Centres and GPs better assess obese individuals as well as better identify who benefits most from having weight loss treatment.
Detailed description
This study will assess various published staging tools to assess the health impacts of obesity on individuals. The aim is to identify benefits and drawbacks, and thus help Obesity Centres and GPs better assess obese individuals as well as better identify who benefits most from having weight loss treatment
Interventions
PROCEDUREBariatric surgery
Bariatric surgery: Gastric bypass, Sleeve gastrectomy, or Gastric banding
Sponsors
Imperial College London
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Morbid obesity * At least 1 year follow-up after bariatric surgery
Exclusion criteria
* N/A
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Obesity Scores After Weight Loss Treatment | Minimum of 1 year follow-up | Changes were measured in the following clinical domains -Airway, Body Mass Index, Cardiovascular risk, Diabetes, Economic, Functional. Gonadal, Body Image. An improvement was considered when any 1 of these domains changes for the positive. Thus, if a patient had an improvement in cardiovascular risk the intervention was considered beneficial even if no other domains changed. Out measure is calculated as the count of participants achieving at least 1 improvement (Count) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Obesity Scores in Various Subgroups | Minimum of 1 year follow-up | Changes in obesity scores in patients with carious co-morbid conditions (eg, type 2 diabetes, sleep apnoea) before bariatric surgery |
Countries
United Kingdom
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Obese Patients Obese patients for Bariatric surgery
Bariatric surgery: Bariatric surgery: Gastric bypass, Sleeve gastrectomy, or Gastric banding | 600 |
| Total | 600 |
Baseline characteristics
| Characteristic | Obese Patients |
|---|---|
| Age, Customized Age | 48 years STANDARD_DEVIATION 6 |
| BMI (kg/m2 ) | 49 kg/m^2 STANDARD_DEVIATION 12 |
| Ethnicity (NIH/OMB) Hispanic or Latino | 0 Participants |
| Ethnicity (NIH/OMB) Not Hispanic or Latino | 600 Participants |
| Ethnicity (NIH/OMB) Unknown or Not Reported | 0 Participants |
| Sex: Female, Male Female | 420 Participants |
| Sex: Female, Male Male | 180 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | 0 / 600 |
| other Total, other adverse events | 30 / 600 |
| serious Total, serious adverse events | 0 / 600 |
Outcome results
Primary
Changes in Obesity Scores After Weight Loss Treatment
Changes were measured in the following clinical domains -Airway, Body Mass Index, Cardiovascular risk, Diabetes, Economic, Functional. Gonadal, Body Image. An improvement was considered when any 1 of these domains changes for the positive. Thus, if a patient had an improvement in cardiovascular risk the intervention was considered beneficial even if no other domains changed. Out measure is calculated as the count of participants achieving at least 1 improvement (Count)
Time frame: Minimum of 1 year follow-up
Population: Obese patients for Bariatric surgery
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Obese Patients | Changes in Obesity Scores After Weight Loss Treatment | 600 Participants |
Secondary
Changes in Obesity Scores in Various Subgroups
Changes in obesity scores in patients with carious co-morbid conditions (eg, type 2 diabetes, sleep apnoea) before bariatric surgery
Time frame: Minimum of 1 year follow-up
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Obese Patients | Changes in Obesity Scores in Various Subgroups | 130 Participants |
| Patients With Sleep Apnea | Changes in Obesity Scores in Various Subgroups | 96 Participants |