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Applications of Realtime Functional Magnetic Resonance Imaging (fMRI )

Applications of Realtime fMRI Phase II

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01111617
Enrollment
400
Registered
2010-04-27
Start date
2014-01-31
Completion date
2023-11-30
Last updated
2024-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Brief summary

The goal of this research program is to determine the potential effectiveness of real-time fMRI training in improving mental control over pain.

Detailed description

A research study that looks at pain and how you experience pain. This research project aims to use virtual reality-based real-time functional Magnetic Resonance Imaging (rtfMRI) to assess brain activation during the experience of pain and while subjects attempt to mentally control their pain response.

Interventions

Patients receive real-time fMRI biofeedback to modulate pain

Sponsors

Stanford University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Age 18-65 * Chronic Pain patient or healthy control * Ability to perform the experimental task

Exclusion criteria

* MRI contraindication (metal implants, claustrophobia, pregnant or planning to become pregnant) * History of psychiatric disorder (at the discretion of the investigator as to whether it interferes with the experimental task) * History of Blistering

Design outcomes

Primary

MeasureTime frame
Pain reduction as measured by visual analog scale (VAS) pain reportWithin the 2 hour feedback session

Secondary

MeasureTime frame
Control of brain activity as measured by fMRI analysisWithin the 2 hour feedback session

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026