Effect of Different Reagents., Oral Anticoagulant Therapy
Conditions
Keywords
Thromboplastin, Prothrombin, Diagnostic Reagent Kits, International Normalized Ratio, Laboratory Tests.
Brief summary
The aim of this study is to assess the effect of Innovin® reagent on laboratory results when compared with the Thromborel® S.
Detailed description
Thromboplastins are the screening tests which are used in the diagnosis of acquired or inherited disorders of the coagulation system but still, alterations between various thromboplastin preparations in the measurements remains a problem.Blood samples are going to drawn from patients receiving and not receiving oral anticoagulant therapy (OAT) during their routine laboratory tests. Samples are subjected to analysis by using Thromborel® S and Innovin® reagents. Mean International Normalized Ratio (INR), prothrombin time and fibrinogen values are going to compared. To further study the importance of this phenomenon the cohort will be divided into three subgroups according to the INR values as Group I: Patients not receiving OAT, Group II: Patients under OAT and INR values in good therapeutic range and Group III: Patients under OAT and INR values over the therapeutic range.
Interventions
None listed
Sponsors
Yuksek Ihtisas Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
Routine control patients receiving and not receiving oral anticoagulant therapy
Exclusion criteria
Hemolytic and/or lipemic samples were excluded.
Countries
Turkey (Türkiye)
Outcome results
None listed