Hydrocephalus, Infant, Newborn Diseases, Nervous System Diseases
Conditions
Keywords
Hydrocephalus, Shunt Dysfunction, Shunt Flow
Brief summary
The study hypothesis is that an ultrasonic flow sensor can accurately measure flow in hydrocephalic shunts. The ultrasonic sensor will measure cerebrospinal fluid drainage in hydrocephalus patients with external ventriculostomies and extra-ventricular drainage systems. The sensor measurements will be compared with the volume of fluid collected by the drainage bag. After a 24-hour measurement period, the doctor will change the drainage bag position to simulate the patient sitting up and leaning back, to see if this temporarily stops flow through the drainage line. This data will show whether the sensor accurately measures typical drainage flows seen in hydrocephalus patients. This research will help develop an implantable flow monitor for pediatric hydrocephalus patients.
Interventions
None listed
Sponsors
National Institute of Neurological Disorders and Stroke (NINDS)
Transonic Systems Inc.
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Diagnosed with hydrocephalus * Instrumented with an Extraventricular drainage system
Exclusion criteria
* Not diagnosed with hydrocephalus * Not instrumented with an extraventricular drainage system
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Volumetric flow of patient cerebrospinal fluid through an Extra-Ventricular Drainage system. | 24 hour-period |
Secondary
| Measure | Time frame |
|---|---|
| Recording of the pressure waveform related to the volumetric flow of patient cerebrospinal fluid through an Extra-Ventricular Drainage system. | 24 hour period |
Countries
United States
Outcome results
None listed