Skip to content

Blood-retinal Barrier Imaging and Neuropsychiatric Sequela in Type 2 Diabetes Mellitus

Blood-retinal Barrier Imaging in Type 2 Diabetes Mellitus: a Window for Blood-brain Barrier Breakdown and Neuropsychiatric Sequela

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01107132
Enrollment
100
Registered
2010-04-20
Start date
2010-05-31
Completion date
Unknown
Last updated
2010-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Macular Edema, Non-Proliferative Diabetic Retinopathy, Type 2 Diabetes Mellitus

Brief summary

In Type 2 Diabetes mellitus patients we will: 1. quantify vasculopathy and blood-retinal barrier (BRB) leakage 2. measure blood-brain barrier (BBB) permeability and neuroanatomical changes 3. correlate BRB pathology with BBB breakdown, inflammatory markers and neuropsychiatric sequela

Interventions

None listed

Sponsors

Soroka University Medical Center
Lead SponsorOTHER

Study design

Observational model
COHORT

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

1. T2DM Patient suffering from Non-Proliferative Diabetic Retinopathy (NPDR), Proliferative Diabetic Retinopathy (PDR) and Diabetic Macular Edema (DME) who are in the clinical database of the ophthalmologic department , above 18 years old at the time of diagnosis and underwent FA examination in the past three years 2. Patients which their medical records are available via a computerized data base Control group: 1. T2DM patients who are in the clinical database of the ophthalmologic department 2. Above 18 years old at the time of diagnosis 3. Underwent FA examination in the past three years and their examination was interpreted as normal, i.e. without suspected diabetic retinopathy

Countries

Israel

Contacts

Primary ContactHadar Shalev, M.D
shalev@bgu.ac.il972506996696

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026