A Comparative Pilot Study Of High-Order Aberrations With Aspheric IOL Models SN60WF and ZCB00

A Comparative Pilot Study Of High-Order Aberrations With Aspheric Intraocular Lens (IOL) Models SN60WF And ZCB00

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01105585

Enrollment

Registered

2010-04-16

Start date

2010-04-30

Completion date

Unknown

Last updated

2012-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataracts

Keywords

Cataracts, aspheric, IOL, ocular aberrations

Brief summary

The purpose of this study was to prospectively compare high-order aberrations between eyes implanted with the AcrySof® Natural IQ (SN60WF) intraocular lens (IOL) versus those implanted with the Tecnis ZCB00 IOL.

Interventions

DEVICETecnis 1-piece Aspheric Acrylic (ZCB00) IOL

Tecnis 1-piece Aspheric Acrylic (ZCB00) intraocular lens implanted in the capsular bag during cataract surgery. The IOL is intended for the lifetime of the patient.

DEVICEAcrySof Natural IQ (SN60WF) IOL

AcrySof Natural IQ (SN60WF) intraocular lens implanted in the capsular bag during cataract surgery. The IOL is intended for the lifetime of the patient.

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Healthy volunteers

Inclusion criteria

* Requires bilateral extraction of cataracts by phacoemulsification followed by implantation of a posterior chamber intraocular lens; * Confirmed absence of pre-existing conditions that could skew the results or present contraindications for the IQ intraocular lens (IOL) or the Tecnis ZCB00 IOL; * \<1 diopter corneal astigmatism preoperatively; * Able to achieve 6.5 mm dilated pupil; * Other protocol-defined inclusion criteria may apply.

Exclusion criteria

* Chronic disease or illness; * Irregular optical aberration; * Amblyopia; * History of corneal disease (e.g., herpes simplex, herpes zoster keratitis, etc.); * Diabetic retinopathy; * Macular degeneration; * History of retinal detachment; * Other surgeries planned at time of cataract removal; * Severe dry eye; * Other protocol-defined

Design outcomes

Primary

Measure	Time frame
Total ocular high-order aberrations	Month 1 postoperative

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026