Liberation From Mechanical Ventilation
Conditions
Brief summary
The purpose of this study is to determine whether chest tubes to drain transudative pleural effusions helps patients come off mechanical ventilation earlier.
Interventions
None listed
Sponsors
Maimonides Medical Center
Study design
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with transudative pleural effusion and requiring mechanical ventilation
Exclusion criteria
* Patients with coagulopathy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Days of Mechanical Ventilatory Support | days |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Standard Care Treatment of pleural effusion with diuresis | 112 |
| Chest Tube Treatment of pleural effusion with diuresis and chest tube | 86 |
| Total | 198 |
Baseline characteristics
| Characteristic | Chest Tube | Standard Care | Total |
|---|---|---|---|
| Age, Categorical <=18 years | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical >=65 years | 76 Participants | 95 Participants | 171 Participants |
| Age, Categorical Between 18 and 65 years | 10 Participants | 17 Participants | 27 Participants |
| Age Continuous | 77 years STANDARD_DEVIATION 11 | 78 years STANDARD_DEVIATION 9 | 78 years STANDARD_DEVIATION 9 |
| Region of Enrollment United States | 86 participants | 112 participants | 198 participants |
| Sex: Female, Male Female | 53 Participants | 71 Participants | 124 Participants |
| Sex: Female, Male Male | 33 Participants | 41 Participants | 74 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | — / — | — / — |
| other Total, other adverse events | 0 / 112 | 0 / 86 |
| serious Total, serious adverse events | 0 / 112 | 0 / 86 |
Outcome results
Primary
Total Days of Mechanical Ventilatory Support
Time frame: days
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Standard Care | Total Days of Mechanical Ventilatory Support | 6.51 days | Standard Deviation 1.5 |
| Chest Tube | Total Days of Mechanical Ventilatory Support | 4.02 days | Standard Deviation 3.9 |