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Prophylactic Selective Lateral Neck Dissection in Patients With Papillary Thyroid Carcinoma

The Effectiveness of Prophylactic Selective Lateral Neck Dissection in Papillary Thyroid Carcinoma Patients With Central Neck Metastasis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01103557
Enrollment
62
Registered
2010-04-14
Start date
Unknown
Completion date
Unknown
Last updated
2010-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphatic Metastasis, Thyroid Neoplasm

Keywords

Papillary thyroid carcinoma with neck metastasis, neck dissection

Brief summary

The purpose of this study is to prospectively analyze the incidence of occult lateral neck metastasis (LNM) and to elucidate the factors that predict LNM in papillary thyroid carcinoma (PTC) with central neck metastasis (CNM) by performing prophylactic selective lateral neck dissection (SND).

Detailed description

The lymphatic drainage pattern of the thyroid is uniform and consistent, and therefore, metastatic patterns are relatively predictable. Initial nodal metastasis in PTC usually occurs in the paratracheal and pretracheal nodes in level VI of the central compartment of the ipsilateral neck and spreads to the lateral cervical lymph nodes. Macroscopic skip metastases to the lateral compartment of the neck in the absence of central disease are uncommon.

Interventions

PROCEDUREprophylactic selective lateral neck dissection

Level II, III, IV lymph node dissection

Sponsors

Pusan National University Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 76 Years
Healthy volunteers
Yes

Inclusion criteria

* Papillary thyroid carcinoma with central neck metastasis * No evidence of lateral neck metastasis as determined by high-resolution neck ultrasonography and computed tomography

Exclusion criteria

* History of previous thyroid operation * Isthmic thyroid lesion

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026