Lymphatic Metastasis, Thyroid Neoplasm
Conditions
Keywords
Papillary thyroid carcinoma with neck metastasis, neck dissection
Brief summary
The purpose of this study is to prospectively analyze the incidence of occult lateral neck metastasis (LNM) and to elucidate the factors that predict LNM in papillary thyroid carcinoma (PTC) with central neck metastasis (CNM) by performing prophylactic selective lateral neck dissection (SND).
Detailed description
The lymphatic drainage pattern of the thyroid is uniform and consistent, and therefore, metastatic patterns are relatively predictable. Initial nodal metastasis in PTC usually occurs in the paratracheal and pretracheal nodes in level VI of the central compartment of the ipsilateral neck and spreads to the lateral cervical lymph nodes. Macroscopic skip metastases to the lateral compartment of the neck in the absence of central disease are uncommon.
Interventions
Level II, III, IV lymph node dissection
Sponsors
Study design
Eligibility
Inclusion criteria
* Papillary thyroid carcinoma with central neck metastasis * No evidence of lateral neck metastasis as determined by high-resolution neck ultrasonography and computed tomography
Exclusion criteria
* History of previous thyroid operation * Isthmic thyroid lesion