Generation of Heparin-induced Thrombocytopenia (HIT)-Antibodies Without Prior Heparin Exposure

Generation of HIT-antibodies Without Prior Heparin Exposure Following Orthopedic Surgery (Subgroup Study) (Change of Coagulation Parameters Under Exposition With New Anticoagulants [Title of the Main Study])

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01102790

Enrollment

160

Registered

2010-04-13

Start date

2010-04-30

Completion date

2010-10-31

Last updated

2010-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heparin-Induced Thrombocytopenia, Thrombosis

Keywords

HIT

Brief summary

The purpose of this study is to determine the HIT-antibody generation without prior heparin-exposure in patients undergoing orthopedic surgery.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Major orthopedic surgery

Exclusion criteria

* Heparin exposure * Infection

Design outcomes

Primary

Measure	Time frame
incidence of HIT-antibodies	between day 5 and day 14 after surgery

Secondary

Measure	Time frame
thromboembolic events	up to 21 days after surgery

Countries

Germany

Contacts

Primary ContactMarc Schindewolf, MD

marcschindewolf@yahoo.com+49 (0)69-6301

Backup ContactEdelgard Lindhoff-Last, Prof.

Lindhoff-Last@em.uni-frankfurt.de+49 (0)69-6301

Outcome results