Vitamin D Status
Conditions
Keywords
Vitamin D, UVB, Frequency, Body surface area, Dose-Response
Brief summary
The purpose of the study is to determine the frequency of UVB radiations necessary to maintain the Vitamin D level during winter time.
Detailed description
The work is addressing vitamin D production after UVB exposure and explore how much UVB radiation which is necessary to maintain a sufficient vitamin D level during the winter period in Denmark. 4 different UVB exposure times and 2 different UVB doses to 2 different body surface areas.
Interventions
RADIATIONBroadband UVB
UVB dose: 1 SED every week
OTHERControl group
No intervention
Sponsors
The Danish Medical Research Council
Bispebjerg Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* 18-65 years * Healthy
Exclusion criteria
* Sun bed use * Holiday or business travel south of 45 degrees latitude during trial * Illness * Drug addiction * Pregnancy * Lactating
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vitamin D (nmol/l) | Monthly during 4 months | Vitamin D measured in a blood sample to define the relationship between frequency of UVB radiations and the Vitamin D level. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Parathyroideahormone (pmol/l) | 4 months | To investigate whether parathyroideahormone is influenced by the UVB radiations. |
Countries
Denmark
Outcome results
None listed