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Progressive Resistance Training in Patients With Class III Obesity

Pilot Study to Determine Feasibility, Acceptance, and Efficacy of a 12-week Progressive Resistance Training Exercise Protocol in Patients With Class III Obesity Preparing for Bariatric Surgery.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01100450
Enrollment
6
Registered
2010-04-09
Start date
2009-09-30
Completion date
2011-03-31
Last updated
2017-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Keywords

bariatric surgery, class III obesity, resistance training, strength, fitness

Brief summary

To test the strength and physical performance outcomes of a 12-week progressive resistance training (PRT) exercise program in a small cohort of patients with Class III obesity who are preparing for bariatric weight loss surgery at Beth Israel Deaconess. The study will also test patient compliance to the 12 week PRT program. Whereas PRT exercise is currently recommended as a part of preoperative clinical care for bariatric surgery patients, little research has been done to measure the acceptance and effectiveness of a standardized PRT exercise protocol for improving health and perioperative care. Preliminary data from this study could be used to justify larger studies and further investigation.

Interventions

BEHAVIORALProgressive Resistance Training

12-week progressive resistance training (PRT) exercise program

Sponsors

Beth Israel Deaconess Medical Center
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Men and women 18-65 years old * A BMI of ≥40 kg/m2 * Considering Weight Loss Surgery at BIDMC * Participating in multidisciplinary preoperative program: * been determined by a mental health professional (i.e., psychologist or social worker) to be well-informed, motivated, and not symptomatic for psychopathology that would put the person at risk for injury or failure with WLS * expressed strong desire for significant weight loss * experienced documented failure of long-term weight loss using nonsurgical methods * been informed of and accepts risks of surgery * Cleared by their primary care physician to be in stable health and capable of moderate level exercise * Willing to comply with expected attendance and participation at all intervention sessions and testing appointments * Has reliable transportation to the intervention location

Exclusion criteria

* Orthopedic limitations that would preclude exercise testing and training

Design outcomes

Primary

MeasureTime frameDescription
6-Minute Walk TestBefore training - Week 1Subjects are instructed to walk from one end to the other of a 30- meter hallway at their own pace, while attempting to cover as much ground as possible in the allotted 6 minutes. Subjects are allowed to stop and rest during the test, but were instructed to resume walking as soon as they felt able to do so. Total distance walked was recorded at the end of the test.

Secondary

MeasureTime frameDescription
Muscle Fatigability TestBefore training-Week 1After appropriate warm-up, subjects performed as many repetitions as possible against a resistance set to 80% or 70% (leg and chest respectively) of their pre-intervention 1-repetition maximum resistance. Fatigability tests measures the ability to sustain a static muscle contraction or make repetitive submaximal dynamic contractions. The test was administered using the leg press and chest press machines (Nautilus Nitro).
1-repetition maximum muscle strength testBefore training-Week 1The subject performs repeated single repetitions of leg press and chest press, separated by 60-second rest periods. Resistance is increased systematically at each repetition until the person's maximum voluntary muscle force cannot move the resistance through the full range of motion. The greatest resistance (measured in lbs.) a person can move through a full range of motion is recorded as the one-repetition maximum. Tests were performed on leg and chest press machines (Nautilus Nitro).

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026