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Resistance Training in Knee Osteoarthritis

Progressive Resistance Training in Women With Knee Osteoarthritis

Status
UNKNOWN
Phases
Phase 2Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01099371
Enrollment
70
Registered
2010-04-07
Start date
2009-02-28
Completion date
2011-02-28
Last updated
2010-05-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

Knee, Osteoarthritis, Exercise

Brief summary

The purpose of this study is to determine whether: 1. Progressive resistance training improves pain and disability 2. Progressive Resistance training improves muscular strength, ability to walk and quality of life

Detailed description

Patients in experimental group participated in a 12-week progressive resistance training using a repetition maximum (RM) exercise in which patients performed 1RM with the maximum bearable weight. Once the 1RM was determined, training was divided into the following regimen: 2 series of 8 repetitions, the first with 50% and the second with 70% of 1RM. The exercises were knee extension and flexion and hip abduction and adduction, all performed in machines. The 1RM load was reevaluated every 2 weeks. The control group remained on a three-month waiting list for physiotherapy. Patients were assessed for pain, function, quality of life, muscle strength and six-minute walk test.

Interventions

OTHERexercise

progressive resistance training

Sponsors

Fundação de Amparo à Pesquisa do Estado de São Paulo
CollaboratorOTHER_GOV
Federal University of São Paulo
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
FEMALE
Age
40 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Woman * Age between 40-70 years old * Pain between 3 and 8 on a 10-point numeric pain scale * Radiographically confirmed knee OA

Exclusion criteria

* Inflammatory diseases or any comorbidity that prohibit exercises, regular physical activity * Trip plans for the next 12 months

Design outcomes

Primary

MeasureTime frameDescription
Pain assessed on a 10-point numeric pain scaleweek 0Scale: visual analog scale

Secondary

MeasureTime frameDescription
Disability assessed on WOMACweek 6Western Ontario McMaster University Osteoarthritis Index Rheumatology An arthritic pain scoring system ranging from 0-no pain/disability to 100-most severe pain/disability WOMAC-pain, WOMAC-function and WOMAC-stifness
Quality of life assessed on the SF-36week 6Questionnaire Short-form-36
Six-minute walk testweek 12To assess distance walked in 6 minutes

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026