A Single-centre, Randomised, Double-blind, Controlled, Parallel-group Study to Evaluate the Effect of a Fermented Dairy Product on Abdominal Distension, Digestive Symptoms and Rectal Sensitivity in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01097993

Enrollment

120

Registered

2010-04-02

Start date

2010-02-28

Completion date

2014-01-31

Last updated

2017-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women With IBS-C

Brief summary

The purpose of this study is to evaluate the effect of a commercially available fermented dairy product containing probiotics (4 weeks, twice a day) on abdominal distension in IBS patients with constipation (IBS-C).

Interventions

OTHER1-fermented dairy product

Arm 1 - Intervention 1 (probiotics)

OTHER2- milk-based non-fermented dairy product (control product)

Arm 2 - Intervention 2 (control)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* female * Age: 18-70

Exclusion criteria

* NA

Design outcomes

Primary

Measure	Time frame
Mean abdominal distension after a 4-week period of product consumption in IBS-C patients	0-4 weeks

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026