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Low Carbohydrate and Conventional Diets Associated to Resistance Training on Muscle Fitness and Health Markers

Combined Effects of Resistance Training and Low Carbohydrate or Conventional Diets on Strength, Muscle Mass, Body Composition, Blood Lipids and Endothelium Function

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01096836
Acronym
LCD-RT
Enrollment
21
Registered
2010-03-31
Start date
2006-09-30
Completion date
2008-08-31
Last updated
2010-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Overweight

Keywords

resistance exercise, body mass index, hypertrophy, endothelial function, blood lipids

Brief summary

The purpose of this study was to compare the effects of two different diets (low carbohydrate - LCD and conventional - CONV) on body composition, strength performance, muscle mass and biomarkers of health in overweight adults submitted to resistance training (RT). It has been hypothesized that LCD would produce higher rates of weight loss and that both diets would be useful to maintain muscle mass and strength and biomarkers of health.

Detailed description

Overweight and obesity prevalence has increased worldwide. Current guidelines recommend health behavior modifications, including better eating habits and regular physical activity (including resistance training - RT) as a strategy to control and prevent the problem. Traditionally, diets poor in energy and fat (conventional diets - CONV) have been recommended to promote losses in body and fat masses; however, there has been recently a growing interest in the academic community to investigate the effects of low carbohydrate diet (LCD) on health outcomes, since this kind of diet appears to be more effective for reducing body mass as compared to CONV. Nevertheless, evidences are scarce regarding the effects of LCD associated to RT on body composition, strength performance, blood lipids, endothelium function and other markers of health, demanding the development of clinical trials aiming to determine the combined health effects of these interventions.

Interventions

OTHERmacronutrient and energy manipulation

Sponsors

Universidade Gama Filho
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* BMI equal or over 25 kg/m2 * resistance trained at least 12 weeks

Exclusion criteria

* upper or lower limbs injury * pregnancy * diabetes * use of ergogenics, stimulants or drugs * history of dislipidemias * arterial hypertension

Design outcomes

Primary

MeasureTime frameDescription
body masseight weeksMeasured always at the same time of the day on a calibrated weight scale

Secondary

MeasureTime frameDescription
Muscle strengtheight weeksMeasured using resistance exercise machines (isotonic) in four exercise movements
Endothelial functioneight weeksMeasured using a two dimensional color spectral Doppler ultrasound equipped with a 14MHz linear transducer. Subject laid down comfortably in the supine position with the right arm slightly abduced. After locating the brachial artery, the transducer was placed on the anteromedial face of the right arm, perpendicular to the centerline of the arm, 5-10 cm above the antecubital fossa, over the artery.
muscle thicknesseseight weeksMeasured with a ultrasoundo bidimensional in Mode B, with a 7,5MHz transducer on the anatomical sites knee extensor muscles and elbow flexors and extensors.
markers of renal functioneight weeksMeasured using conventional and satandardized laboratory methods with subjects fasting for 12 hours
body compositioneight weeksMeasured with skinfold calipers and using prediction equations to determine body fat and lean body mass.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026