Early Incidence of Occupational Asthma Among Bakers, Pastry-makers and Hairdressers

Evolution of the Incidence of Occupational Asthma at the Beginning of the Activity of Young Bakers, Pastry-makers and Hairdressers, and Exploration of Its Risk Factors

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01096537

Acronym

ABCD

Enrollment

866

Registered

2010-03-31

Start date

2008-12-31

Completion date

2010-06-30

Last updated

2016-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Occupational Asthma

Keywords

incidence, young workers, occupations at risk, public health, epidemiology, polymorphisms, gentic

Brief summary

Background: Occupational exposures are thought to be responsible for 10-15% of new-onset asthma cases in adults, with disparities across sectors. Because most of the data are derived from registries and cross-sectional studies, little is known about incidence of occupational asthma (OA) during the first years after inception of exposure. This study focuses on this early asthma onset period among young workers in the bakery, pastry making and hairdressing sectors in order to assess early incidence of OA in these at risk occupations according to exposure duration, and to identify risk factors of OA. Methods: This study is a longitudinal retrospective study with a nested case-control to identify risk factors of OA. The assessment of incidence evolution is made by exploring a series of promotions (or retrospective cohorts) with increasing duration since at work. The study population is composed of subjects who graduated between 2001 and 2006 in sectors where they experience exposure to organic or inorganic allergenic or irritant compounds (with an objective of 150 subjects by year) and 250 young workers with no specific occupational exposure. This study is a descriptive, monocentric, longitudinal and retrospective study with cross-sectional measurements.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* for the exposed group: to be graduated between 2001 and 2006 from nine vocational schools in Lorraine, North-Eastern France * for the non-exposed group: to be graduated in 2001 in the sale or the food sectors (butcher, pork butcher, caterer, cook job,…) from the same vocational schools

Exclusion criteria

* asthma diagnosed before apprenticeship * for the non-exposed group: to have worked previously or later in a sector at risk with OA

Design outcomes

Primary

Measure	Time frame
The early incidence of OA among young workers according to their sector of activity and exposure duration.	3-6 months after tle last inclusion

Secondary

Measure	Time frame
The identification of risk factors of OA.	3-6 months after the last inclusion

Countries

France

Outcome results